0:48:00m – Spoken journal of #ActuallyAutistic #LivedExperience by a #LateDX #Senior – Today? Probabilities, possibilities, prevalence, and puissance; brought to you by this assonance-hole!
Distributed Core Processing and Pattern Management: An Autistic Naturalist’s Theory of Locus and Mechanism
This paper presents a novel hypothesis for the locus and mechanism of what is traditionally termed “working memory,” reframed as “distributed core processing.” The genesis and development of this model arise not from conventional laboratory inquiry, but from sustained naturalistic observation and intensive, self-directed thought experiments over a lifetime. The author, an autistic individual, proposes that enhanced pattern management and acute environmental data processing—hallmarks of autistic cognition—confer insight into distributed brain network behaviors. The paper outlines the theory, its foundations, and the scientific literature now converging to validate these intuitions. It concludes with a critique of rhetorical aversion to neurodivergent difference, arguing such aversion diminishes global innovation capacity.
Longitudinal Safety: An intentional gap? (policy)
The integration of longitudinal genetic and epigenetic studies into routine pharmaceutical safety evaluation is a critical and glaring knowledge gap that demands urgent attention within drug development and post-marketing surveillance pipelines. Despite the rapid advancement in genetic, epigenetic, and neuro- sciences enabling unprecedented molecular insight, current safety assessments largely overlook the cumulative and nuanced molecular impacts of chronic drug exposure, thereby potentially perpetuating unforeseen risks to patient safety and public health. This lack of progressive integration underscores profound ethical and scientific shortcomings that risk undermining both patient trust and optimal therapeutic outcomes.
Ramble – 09242025
58:42m, spoken audio, daily journal of a senior autistic; life, the universe and everything, bounded by patterns, science, and aspiration for the future. Hope lives here, oddly enough.
The truth about Autism (#Science, bitches)
10m spoken audio; short review of current science on the realities of #autism as a normal, natural, healthy diversity within the human genome. (Diversity is requisite for a healthy genome.)
Contingent Uniqueness: Extending the Rare Earth Solution to the Fermi Paradox Through Biochemical Contingency and Cross-Disciplinary Synthesis
Introduction The Fermi Paradox presents a fundamental contradiction between theoretical expectations and empirical evidence: given the vast number of potentially habitable planets and the apparent ease with which life emerged on Earth, why do we find no evidence of extraterrestrial intelligence? The Rare Earth hypothesis offers one solution by proposing that complex life requires extraordinarily specific conditions, but recent advances in origin-of-life research, systems chemistry, and cross-disciplinary astrobiology suggest this explanation remains incomplete (Fermi paradox, 2025; Alternative Pathways in Astrobiology, 2024). This paper proposes a “contingent uniqueness” framework that extends the Rare Earth hypothesis by integrating biochemical contingency theory, non-biomolecular […]
Father-In-Law, I’mma read you for filth.
13m spoken audio; partner finally has had enough with the bullying of his father. I support my partner in making choices that protect his mind and body. This the letter *I* sent once the fifteen year process of partner’s decision making has come to its fruition.
Oh come at me for it, because #TeamHoneyBadger DGAF and will happily teach you the lesson as many times as you need it.
Understanding Cycles of Systemic Violence, Supremacist Ideology, and Ecological Crisis:
This paper explores the interconnected, recurrent global patterns of systemic violence against marginalized outgroups. Rooted in historical legacies of eugenics, white supremacy, and transgenerational trauma, these cycles are amplified by economic inequality, misinformation ecosystems, legal and institutional frameworks, psychological identity dynamics, and ecological crises. Recognizing these patterns is essential for approaches that promote justice, sustainable coexistence, and planetary survival.
Systems Analysis: Our Present Moment (global/usa)
35m contextually focused thoughts on this moment and the most important thing anyone wanting humanity to survive it really need to start putting into practice (and why).