The Bio-Social Loop: How Culture & Economy Engrave Hate in Our DNA

The accelerating crisis of fascism, racism, and “dehumanizing” behaviors is more than a product of conscious prejudice or institutional design—it is an emergent, biologically mediated epidemic produced by the interplay of cultural, economic, and societal structures with the human genome and neurobiology (Stringhini et al., 2022; Krieger et al., 2022; Kuzawa & Sweet, 2021). New research in neuroscience and social epigenetics demonstrates that these structural forces shape us at the molecular level, perpetuating patterns of aggression, exclusion, and social unraveling that threaten collective stability (Kuzawa & Sweet, 2021; Krieger et al., 2022).

A Worthy Labor

There is a simple and compelling truth established by the sciences: universal reality is a system of systems, and all life within it exists only in relationship and interdependence with its surroundings. This conclusion is not just philosophical speculation; it is supported by disciplines such as physics, biology, and complex systems theory. Denying this reality has contributed directly to human suffering, social turmoil, and ecological crises, which continue to threaten our collective future. The observable universe, from subatomic particles to galaxies and biospheres, is characterized by nested systems that interact and rely on each other. No organism survives in isolation. […]

The Strength of Weak Ties Across Disciplines: Connectivity, Plasticity, Novelty, & the Imperative for Global Solutions

The sociological theory of weak ties, introduced by Mark Granovetter in 1973, reveals that infrequent, low-intensity social connections act as vital bridges that link otherwise disconnected social groups. These weak ties facilitate the flow of novel information, resources, and opportunities, supporting innovation and adaptability within social networks (Granovetter, 1973). Over time, this foundational insight has found compelling parallels across disciplines including technology, neuroscience, quantum physics, organic chemistry, machine learning, and cloud computing. These interdisciplinary connections expose shared principles of connectivity, plasticity, and novelty underpinning both natural and human-created complex systems.

The Ventromedial Hypothalamus, Autism, cPTSD, and Type 2 Diabetes: Piecing Together the Neuroendocrine Puzzle

Living as an autistic human with cPTSD, my personal health journey has always intersected with questions about the brain, stress, and physical illness. Recent neuroscience is finally exposing the depth of mind-body connections in conditions like type 2 diabetes (T2D)—and for people wired differently, like those on the autism spectrum or living with the scars of toxic stress, these findings feel especially urgent. A new mechanism, outlined in Lin et al. (2025), peels back the lid on how metformin, the most common diabetes drug, directly interacts with the brain’s ventromedial hypothalamus (VMH) to control blood sugar. This opens new theories about the unique diabetes risks faced by neurodivergent and trauma-affected populations and whether treatment responses might also diverge.

Human Cognitive Diversity as Adaptive Radiation: Genomic and Neurodivergent Pathways to Species Dominance

Rapid radiations, in which bursts of diversification yield disproportionate contributions to extant biodiversity, underlie most of the known diversity of life (Wiens & Moen, 2025). This principle holds across clades of animals, plants, fungi, and protists. We argue that a parallel process manifests in humans: our global dominance as an apex mammalian species derives from rapid internal diversification of cognition, behavior, and social interaction styles. Drawing on evolutionary genomics, epigenetics, and neuroscience, we propose that neurodiversity—including autism and related neurodivergent profiles—constitutes an adaptive radiation within a single species, sustaining variation that enables resilience, innovation, and ecological mastery. We synthesize evolutionary biology with human neuroscience to suggest that the same mechanisms responsible for generating flowering plant and arthropod hyperdiversity also operate, at a psychological and genomic scale, in Homo sapiens.